Top 25 College Hoops Picks Against the Spread – Wednesday, February 12

Published 11:11 pm Tuesday, February 11, 2025

The California Golden Bears versus the Duke Blue Devils is one of five games on the college basketball slate on Wednesday that includes a ranked team in play. We offer ATS picks for each contest in the article below.

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AP Top 25 Picks ATS Today

Villanova Wildcats vs. No. 12 St. John’s Red Storm

Spread Prediction

  • Computer Prediction: St. John’s 74, Villanova 70
  • Projected Favorite: St. John’s by 3.9 points
  • Pick ATS: St. John’s (-2.5)

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Bet on the Villanova-St. John’s spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 6 p.m. ET
  • Location: Bryn Mawr, Pennsylvania
  • Venue: The William B. Finneran Pavilion
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

South Carolina Gamecocks vs. No. 25 Ole Miss Rebels

Spread Prediction

  • Computer Prediction: Ole Miss 76, South Carolina 67
  • Projected Favorite: Ole Miss by 8.3 points
  • Pick ATS: Ole Miss (-4.5)

Bet on the South Carolina-Ole Miss spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 7 p.m. ET
  • Location: Columbia, South Carolina
  • Venue: Colonial Life Arena
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 13 Texas Tech Red Raiders vs. Arizona State Sun Devils

Spread Prediction

  • Computer Prediction: Texas Tech 79, Arizona State 68
  • Projected Favorite: Texas Tech by 11.0 points
  • Pick ATS: Arizona State (+15.5)

Bet on the Texas Tech-Arizona State spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 9 p.m. ET
  • Location: Lubbock, Texas
  • Venue: United Supermarkets Arena
  • TV Channel: CBS Sports Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 2 Duke Blue Devils vs. California Golden Bears

Spread Prediction

  • Computer Prediction: Duke 84, Cal 62
  • Projected Favorite: Duke by 22.1 points
  • Pick ATS: Cal (+23.5)

Bet on the Duke-Cal spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 9 p.m. ET
  • Location: Durham, North Carolina
  • Venue: Cameron Indoor Stadium
  • TV Channel: ACC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 15 Missouri Tigers vs. Oklahoma Sooners

Spread Prediction

  • Computer Prediction: Missouri 79, Oklahoma 72
  • Projected Favorite: Missouri by 6.6 points
  • Pick ATS: Oklahoma (+8.5)

Bet on the Missouri-Oklahoma spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 9 p.m. ET
  • Location: Columbia, Missouri
  • Venue: Mizzou Arena
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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